I'm beginning to think the "tune" is the sum of many factors. We use to think of changing the tune by powder charge only, then "tuners" were added as a variable. I've also long believed that changing bullet jam is essentially the equivalent of a couple tenths of powder, And I wouldn't be surprised if neck tension changes couldn't be mirrored by power changes too.
That said, if you look at Varmint Al's modeling, where the front rest is placed also seems to affect tune. I had a 1995 Kelbly-built rifle with their weight system. The common opinion was that if you put in the rear weight --about 2 pounds -- all you got was a butt-heavy rifle. Yes. Well, if you then moved the front rest back, less of the weight was on the rear bag, and it shot lights-out. In fact, it shot better as a HV (rest moved back) than as a LV. Of course, all the other variables (powder, jam, neck tension, etc.) were the same.
So, I don't think there is any theoretical *ideal* balance. Obviously, you don't want the rifle too light on either of the bags. But I believe weight distribution (i.e., bag loading) is just one of the tune factors.
FWIW, & that's probably not much. (FWIWBTPNM, but not NSOLWFMO)