No.
The ladder tests identify loads which, contrary to logical expectations, coincide at the same point of aim. Listening to sages on this site, it is likely that the trauma of firing these particular loads results in them exiting the barrel just after it has pased thru peak upward vibration. As a result, the progressive downward movement of the barrel compensates for the progressive flatter shooting of the loads as velocities go up.
On the other hand. it might occasionally mean that you have reached Oh Dear loading density & you just aren't getting any more velocity with your incremental load weight. Generally, it's unlikely that you go past this point too often.
Ladder load selection is the concept that permits centrefire benchrest shooters to load with powder throwers, rather than more precise devices, as they know that they've achieved a sweet spot that will stand loads being plus or minus a tad. This is achieved by going with the midpoint load of the coincident grouping shots.
Sweet spot loads quite possibly will not have the ultimate velocity spreads & standard deviations compared to others in the same loading sequence, but will be selected because they are in that pattern of tight vertical grouping. This doesn't mean that they aren't well crafted loads nevertheless.
Now, what interests me as a retired centrefire benchrester in good standing is whether you ladder test at 100 yards, with the mathematical probability that the 200 yards grouping will have an element of vertical or test at 200 in the expectation that most shoot better at 100. Or do you take it the next step & use a tuner to fair out the ladder loads.