I would strongly suggest that you stay away from 4227 of any kind. I haven't used them all, but why take the risk of losing your eyesight or worse. N120 isn't quite as volatile, but you must be careful with it as well. I've tried these 2 as well as H4198, N130 and RE7 in the 30PPC. While you can push velocities into the 3000's easily with N120 and Re7, you will be pushing the envelope. I've had my best accuracy with the slower burning powders anyway, RE7 being the best. I can push it to 2900 with a 115gr bullet, but the recoil and jump in my 10.5lb rifle is too much for an entire agg. It aggs best at around 2800.